Needle-Free Botox: Revolutionizing the Global Beauty and Medical Aesthetics Industry
KolorPen has developed a cutting-edge medical device, the first of its kind worldwide, allowing liquids to be delivered through the skin without the use of needles or syringes. This revolutionary, non-invasive, and painless technology provides a level of precision unmatched by traditional methods, significantly improving both treatment outcomes and the overall patient experience.
Market-Ready, Proven Technology
KolorPen's technology has been successfully validated through multiple POC procedures, demonstrating its effectiveness and readiness for commercialization in real-world applications such as permanent makeup and medical aesthetic treatments. The company anticipates reaching full commercialization within 12 months.
Approved USA and Europe patents
The company holds a key US patent and has six additional patents pending, giving it a significant technological edge and protecting its innovative solutions in the global market.
Strategic Partnerships with Leading Global Cosmetics and Aesthetic Companies:
KolorPen™ has established strong collaborative relationships with key industry leaders. The company is working closely with:
Grants and Funding
KolorPen's innovative product has been thoroughly evaluated by a leading global aesthetic and cosmetic conglomerate, which has directly invested in KolorPen's R&D and committed additional resources internally to support its development. In addition, the company has received a substantial grant from the Israel Innovation Authority.
Expert Leadership and Proven Track Record
KolorPen's leadership team combines decades of experience in high-tech product development, medical aesthetics, and global market expansion. Founder and Chairman Reuven Gamliel brings over 35 years of expertise in high-tech innovation, while Dr. Yoram Eshel, CEO and PhD in Medical Physics, has 30 years of experience in leading aesthetic medical device companies. The team is further strengthened by Dr. Marina Landau, a world-renowned dermatologist and expert in skin rejuvenation, and Dr. Yitzhak Weissman, a physicist with extensive experience in quantum mechanics and optics. This powerful combination of scientific and business expertise positions KolorPen for innovation, strategic growth, and success in the global market.
The Need
Ttraditional needle-based aesthetic and medical procedures are widely used for treatments such as Botox and hyaluronic acid injections, skin rejuvenation, and permanent makeup (e.g., microblading, eyeliner tattooing, lip blushing).
However, these conventional methods come with several significant drawbacks that create a need for a safer, more effective alternative:
1. Uneven Application: Traditional needles struggle to deliver liquids evenly along a surface, which is crucial for applications like lip blushing and skin treatments.
2. Inconsistent Surface Coverage: Achieving uniform distribution of liquids over larger areas, such as the neck, is difficult with needle-based injections, leading to inconsistent treatment results.
3. Lack of Dose Control: Conventional methods cannot precisely control the depth of penetration, the amount of liquid injected, or the temperature of the solution, which can impact treatment accuracy and effectiveness.
4. Patient Discomfort and Risks: Needle-based treatments often result in discomfort, pain, fear, and the risk of infection, all of which can negatively affect the patient experience.
The Solution: KolorPen’s Revolutionary Needle-Free Technology
KolorPen provides a groundbreaking solution with its needle-free, repetitive nano-injection technology, enabling precise, safe, and painless delivery of liquids such as Botox, fillers, pigments, and more. By utilizing piezoelectric technology, KolorPen's devices offer unparalleled control over droplet size, speed, volume, depth, and temperature, resulting in more accurate and consistent treatments for both aesthetic and medical applications.
Key Features of KolorPen’s Solution:
1. Repetitive Nano-Injection: Unlike traditional methods, KolorPen’s device can perform repetitive injections at up to 100 droplets per second, enabling continuous application of the liquid and significantly speeding up procedures while maintaining high precision.
2. Precision and Control: KolorPen’s technology allows for fine-tuned control over the injection process, ensuring accurate and consistent application of liquids such as Botox, hyaluronic acid, pigments, and creams. This results in more even surface coverage and uniform treatments.
3. No Needles, No Pain: By eliminating needles, KolorPen provides a painless and non-invasive alternative, reducing discomfort and fear for patients while also minimizing the risk of infection and cross-contamination.
4. Versatile Applications: The technology is adaptable across multiple aesthetic and medical procedures, from permanent makeup and scar camouflage to medical applications such as Botox, PRP, skin tightening, and fat destruction.
5. Temperature Control: KolorPen’s system can also heat the liquid for specific treatments, enhancing the effectiveness of procedures such as cellulite reduction and skin rejuvenation.
Clinical Evidence and Results:
KolorPen has demonstrated successful clinical results in various treatments, including:
Permanent makeup (e.g., eyebrow tattooing and lip blushing):
Scar camouflage:
Tattoos:
Spider vein treatments:
Hair transplantation anaesthesia:
Pigment and cream insertion with accurate depth and volume control:
The Technology
KolorPen™ is a cutting-edge, needle-free nano-injection device that utilizes piezoelectric energy to convert liquids into nano-droplets, which are then delivered into the skin at high velocity. This method offers both precision and speed, making it ideal for a range of applications, including micro-pigmentation, cosmetic treatments, and medical aesthetics. By precisely controlling the electric voltage applied to the piezoelectric crystal, the system achieves exceptional accuracy in regulating droplet speed, volume, and depth. As a result, the injection process is highly controlled and tailored for optimal treatment outcomes. The system is capable of delivering various materials, such as:
The Products
KolorPen has developed three distinct products, each designed for different markets and applications, all utilizing the same basic technology:
Since the products address different anatomical needs, they penetrate to different depths:
The medical products (SkinJet™ and ThermaJet™) are designed with a disposable component that is replaced between patients. This ensures the highest standards of sterility and prevents any risk of cross-contamination during treatments.
Product Development Status:
The KolorJet™ is currently a fully functional product, with all parameters performing as expected. The next steps involve finalizing the industrial design for its exterior and transitioning the product to mass manufacturing.
Several proof-of-concept procedures were conducted using KolorJet™ to demonstrate its technological capabilities. These procedures were tested on volunteers in the permanent makeup and medical aesthetics markets.
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Mr. Gamliel is the founder and CEO of KolorPen Ltd. He has over 35 years of experience in the high-tech industry, including product development, marketing, and strategic partnerships. He has also acquired knowledge and experience in the field of cosmetics and medical aesthetics. He used his scientific knowledge to develop the Kolorphan needle-free micro-droplet injection system.
Gamliel was the founder, chairman, and president of Gambit Computer Communications Ltd. Under his leadership, Gambit went public on the Tel Aviv Stock Exchange.
Mr. Gamliel holds a bachelor’s degree in computer and electronic engineering from the Technion in Haifa, Israel.
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PhD. medical physics from Tel Aviv University (1994). 25 years of experience in medical device companies in executive positions. CEO from inception to more than $20M in sales. Experience in Marketing and sales, including establishment of direct sales forces, distribution channels, worldwide service division and CRM. R&D of multidisciplinary first in the market technologies. Organization built-up from a small start-up to a structured company with more than 100 employees in 5 countries.
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Dr. Landau is a senior dermatologist who graduated from the Faculty of Medicine at Ben Gurion University, completed a residency in dermatology at Sourasky Medical Center Tel Aviv (Ichilov Hospital) and is a doctor (retired) in the IDF Medical Corps. After her internship, Dr. Landau underwent professional training in the USA and Canada.
Dr. Landau is considered one of the leaders in the world in the field of medical treatments for skin rejuvenation
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Mr. Sawaed, holding a B.Sc. in Physics and Biomedical Engineering, stands as a seasoned senior developer excelling in software development and intricate communication applications. His expertise extends across Android and IOS App development, Java, and the creation of complex wireless models. Notably, Sawaed pioneered the revolutionary KolorPen Wireless Communication model. Proficient in navigating various operating systems like MAC-OS, Windows, and Linux, he ensures adaptable solutions across platforms. Recognized as a visionary strategist, he is committed to crafting innovative solutions that redefine technological boundaries. An effective communicator, Sawaed adeptly translates intricate technical concepts for diverse audiences.
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Dr. Weissman educated as a physicist and obtained his Ph.D Degree from Tel Aviv University (Israel) in 1980. Dr. Weissman scientific career lasted for about 30 years and was devoted to research in quantum mechanics and optics. During this period Dr. Weissman published over 30 papers in the scientific literature and a scientific books. Dr. Weissman scientific activity gave way to technological R&D, and his publications were replaced by patents. Dr. Weissman skills include creativity and initiative, Innovations, excellent capability in fast and efficient proof of concept and feasibility study, ability to analyze and design complex interdisciplinary systems.
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